Why does the shape of a protein matter?
- To build a brick building you need all bricks to complement each other .....to scaffold upon each other to make a strong structure. Just like that amino acids, which are the small bricks that make protein need to arrange in a certain manner to make certain proteins.
How does protein folding occur?😮
As mentioned above proteins are made when amino acids are arranged in a certain manner in long chains. These chains -ofcourse have to fold to make up a protein shapes. This happens spontaneously and due to repulsion between amino acids and watery environments in the cells. Cells help the protein to fold with the help of chaperone proteins ( chaperone of course after the drivers of the process). These proteins help to prevent misfolding .
Why does it even matter?🧐
The type of shape that the protein has determines its functions.
- It can act as an enzyme.
- It build up hair or nails .
- It can be used to transport oxygen in the blood through hemoglobin.
- It can act as an antibody.
When does folding go wrong?
Misfolding of proteins can cause the proteins to attach together and damage other cells in some cases it can extend to:
- Cystic Fibrosis
- Alzheimer’s disease
- Parkisons disease
If you want any other science concept that seems complex or have any questions about this topic don´t hesitate to comment :) 💙
Hey great job!! I would like to know more about cystic fibrosis.
ReplyDeleteThank you!!! I would love to make one about cystic fibrosis.
ReplyDeleteAfter Alzheimer , Parkinson's disease is on rise ..what do u think is it something to do with the environmental factors or increased awareness or improved diagnosis
ReplyDelete